Down Syndrome
Down Syndrome


Comparison of a physiognomy of a male who began treatment late at the age 9 1/2 (Before), and his condition at the age 10 1/2 (After).

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7 years old   8 years old
     
 
9 years old   10 years old
     
The pictures show the transformation from an uncontrolled mimicry, to a glassy stare, to a sociable facial expression



Progress of expressive (physiognomic) changes of a Down syndrome child
 
 
 
Before
a) at 1 year of age
  During
b) at two years of age
  After
c)at four years of age



Highly stigmatized Down syndrome girl from a high Alpine valley who, at 2.5 years of age,
         
 
 
was unable to speak; was restless, worrisome, and unmanageable   six months after the beginning of treatment, the child already maintains eye contact and pays attention   After four years of treatment – at 6 1/2 years of age, and after attending a normal kindergarten, the child speaks German and Italian, is enrolled in primary school on a trial basis.



Progress of a Down syndrome boy at:
         
   
Before
1 1/1 years of age
  During
at three years of age
  After
at nine years of age



Down syndrome boy with chronic infections
     
 
at the beginning of treatment
 
five months later



Down syndrome boy with chronic infections
     
 
Before
highly stigmatized facial expression
 
After
considerable normalization of facial expression after five years of treatment



Down syndrome girl at seven months of age before treatment
     
 
Before
 
After
after 4.5 years of treatment



Photographs of a Down syndrome boy between two and seven years of age (a-f) from the family album
         
   
         
   
         



Characteristic change of appearance, mimicry, and pigmentation, of four Down syndrome children under treatment from age two to eight
 



Physiognomy and appearance (phenotype) of Down syndrome children treated from ages five to fourteen
 



Facial expression and appearance of Down syndrome children under treatment since one year of age
 



Representative cross-section of the appearance of treated Down syndrome boys from age four to fourteen
 



BOY : Marcus
         
   
Marcus as an infant   Still unable to walk   Marcus on the potty

 
Marcus and his younger sister.
 
The siblings in a sleeping bag

 
 
 
Play is hard work for the small boy. Marcus “works” with educational toys (coordinating, assigning).

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